On the subject of the placebo effect in the field of medicine, our evidence states: ‘A 2010 Cochrane systematic review published by Hróbjartsson & Gøtzsche, which confirms and modifies their previous work, over 200 trials investigating 60 clinical conditions were included. Placebo interventions were again not found to have important clinical effects in general but may influence patient-reported outcomes in some situations, especially pain and nausea, although it was "difficult to distinguish patient-reported effects of placebo from response bias". The pooled relative risk they calculated for placebo was 0.93 (effect of only 7%) but significant.’

The statistically relevant trials we conducted for Migraine Escape® - with regard to the number of trial participants vs migraine sufferers - demonstrated an efficacy rating of 97.2%, sufficiently high enough to overcome any placebo effect.



Cochrane Database Syst Rev. 2010 Jan 20;(1):CD003974. doi: 10.1002/14651858.CD003974.pub3.